I believe they should but they were not working and they still don't. I tried configuring them but it didn't work. I was able to see from the command line which keys were being pressed but the expected response (for e.g. reduce or increase screen brightness or sound volume) was not working. It was some time ago, will have to look it up again, but should you have any suggestion, feel free to share - I am willing to try.
I thought such keys should work by default in Gnome, you can try configuring your keyboard and see what happens.
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