I did an upgrade to 10.10 early this month from 10.04 (which I've used since April) using the alternate amd64 cd. Running on HP 6715b.
IMHO 10.10 is unstable...saw my first freeze there after a day of use! The first thing you notice is increased CPU usage even with no user programs running - this is also on the net so I guess I'm not the only observer. Word of advice: test on a box before you 'jump ship'. Maybe its my hardware platform, but I formatted and went back to 10.04 and my machine is a happy penguin.