I haven't and I only know how to do these things with Exim as the MTA.
However, I Gugu-ed and found this for you:

http://www.howtoforge.com/how-to-set-up-a-postfix-autoresponder-with-autoresponse


This MUST be able to work.



On 26 May 2014 11:46, Peter Mugoh <pkmugoh@gmail.com> wrote:
Skunks,

Has anyone tried to create an Out Of Office Auto Reply on CentOS 6x Linux with Postfix MTA successfully?

Thanks and regards,

Peter Mugoh

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Best regards,
Odhiambo WASHINGTON,
Nairobi,KE
+254733744121/+254722743223
"I can't hear you -- I'm using the scrambler."